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美国首例因严重COVID19感染导致肺

来源:淋床医学翻译:浪花一朵朵

FirstSuccessfulLungTransplantationforPulmonaryFibrosisDuetoSevereCOVID-19InfectionintheUS

美国首例因严重COVID-19感染导致肺纤维化的肺移植成功C.Kurihara,andA.Bharat.NorthwesternUniversityFeinbergSchoolofMedicine,Chicago,IL.Introduction:Lungtransplantationcanpotentiallybealife-savingtreatmentforpatientswithnon-resolvingCOVID-19acuterespiratorydistresssyndrome.ConcernslimitingtransplantincluderecurrenceofSARS-CoV-2infectionintheallograft,technicalchallengesimposedbyviralmediatedinjurytothenativelung.Here,wereportthefirstsuccessfullungtransplantationinapatientwithnon-resolvingCOVID-19associatedacuterespiratorydistresssyndromeintheUnitedStates.导言:肺移植可能是一种挽救未解决的COVID-19急性呼吸窘迫综合征患者生命的治疗方法。限制移植的问题包括:同种异体移植中SARS-CoV-2感染的复发,病毒介导的天然肺损伤带来的技术挑战。在这里,我们报道了美国首例未解决的COVID-19相关急性呼吸窘迫综合征患者的肺移植成功。CaseReport:Therecipientwasa28-yearoldfemalewithpastmedicalhistoryofneuromyelitisopticatreatedwithmycophenolateandrituximabwhodevelopedCOVIDpneumonialeadingacuterespiratorydistresssyndrome.Thepatientwasintubatedfor8dayswithpronepriortoinitiationofVVECMO.HerECMOcoursewas


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